Pedro Ervilha Pereira 

"After graduating with an MSc in Molecular Medicine at Imperial College, London, I started pursuing my PhD at Ghent University, here at the Dermaut Lab. 
My current work focuses on the study of a unique and novel mutation in the TARDBP gene (coding for the protein TDP-43, found to be highly involved with neurodegenerative conditions such as ALS). 
Our hope is to unravel the mechanisms behind the unusual and intriguing symptoms shown by patients with this variant, ultimately paving the way to a better understanding of TDP-43-associated neurodegenerative diseases."


 C-terminal frameshift variant of TDP-43 with pronounced aggregation-propensity causes rimmed vacuole myopathy but not ALS/FTD

Ervilha Pereira P*, Schuermans N*, Meylemans A, LeBlanc P, Versluys L, Copley KE, Rubien JD, Altheimer C, Peetermans M, Debackere E, Vanakker O, Janssens S, Baets J, Verhoeven K, Lammens M, Symoens S, De Paepe B, Barmada SJ, Shorter J, De Bleecker JL, Bogaert E, Dermaut B. *equal contribution
Acta Neuropathol. 2023 Mar 31. doi: 10.1007/s00401-023-02565-1. PMID: 37000196. 

Expanding the TDP-43 Proteinopathy Pathway From Neurons to Muscle: Physiological and Pathophysiological Functions.

Versluys L, Ervilha Pereira P, Schuermans N, De Paepe B, De Bleecker JL, Bogaert E, Dermaut B.

Front Neurosci. 2022 Feb 3;16:815765. doi: 10.3389/fnins.2022.815765. eCollection 2022.

PMID: 35185458